PDF .NET - API allows you to do - process forms, work with multidigital signatures, get and set metadata, search for text, process text and pages, work with pages, manage annotations, convert, add or remove bookmarks and watermarks, edit attachments, handle custom fonts and much more other.

PDF .NET is a native library for Developers (C# , VB.NET) and can be used to read, convert, edit and manipulate of PDF documents.
No Adobe, No MS Office.